The postdoctoral researcher will be working in multidisciplinary projects investigating fungal secondary metabolism. The research program aims at chemical profiling and identification of bioactive metabolites from different fungi. The candidate will have basic fungal (preferred) or bacterial microbiology experience, and although desired, training in molecular techniques and genome mining can be provided.
The Keller Group is based in the Department of Medical Microbiology and Immunology at the University of Wisconsin-Madison. The research programs within the group focus on (i) Regulatory mechanisms of biosynthetic gene clusters and synthetic expression of these clusters, (ii) Tools and advances in the study of the human pathogen Aspergillus fumigatus, (iii) Bioinformatic tools to identify metabolic genes and clusters in fungi, (iv) Identification of Cross-kingdom small molecule communication, (v) elucidating the ecological role of fungal secondary metabolites.
The group is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.
For more information visit https://sites.google.com/view/kellerlabuw/keller-lab-home
Position available immediately or until filled. Enquiries can be made to Professor Nancy Keller; email: npkeller@wisc.edu
Please include in your email:
- Application letter describing the required experience for the position
- Curriculum vitae
- Contact details of three referees who may be asked for a reference letter
The postdoctoral researcher will be working in a leading group in the regulation of fungal metabolism and will perform the metabolomics investigation of different fungal species. The lab is equipped with analytical/preparative HPLC–DAD and UHPLC–HRMS (Orbitrap), and has access to the NMR facilities in the departments of Chemistry and Biochemistry.
- PhD in life sciences (Natural Product Chemistry, Organic Chemistry, Microbiology or equivalent Degree).
- Knowledge of fungal (preferred)/bacterial (acceptable)/plant (acceptable) secondary metabolism, metabolites extraction/isolation/purification, analytical chemistry.
- Knowledge of basic statistics and multivariate data analysis.
- Work experience of NMR spectroscopy and Mass spectrometry.
- Work experience of isolation and purification of natural products.
- Work experience of structure identification and determination of metabolites through NMR or MS/MS.
- Work experience with standard microbiology techniques.
- Work experience in bioinformatics analysis and genome mining.
- Excellent communication, presentation and writing skills.
- Strong ability to work in a team.
Enquiries can be made to Professor Nancy Keller; email: npkeller@wisc.edu
