Michael Mullowney

HOT TOPICS IN PHARMACOGNOSY: The Evolution of Dolastatin 10 Derivatives as Sources of ADC Warheads

February 8, 2021 by Michael Mullowney

By David Newman, DPhil Though natural product chemists who specialize in marine-sourced agents are usually aware of the contribution of structures based upon dolastatin 10 as warheads in antibody-drug conjugates (ADCs), targeted against cancers of varying etiologies, the majority of…

Investing in Natural Products

February 8, 2021 by Michael Mullowney

Published as a SIDEBAR to: HOT TOPICS IN PHARMACOGNOSY: The Evolution of Dolastatin 10 Derivatives as Sources of ADC Warheads By David Newman, DPhil By Cedric Pearce, PhD After 25 years of working as a scientist in increasingly entrepreneurial…

O’Keefe Interviewed for BBC Documentary

December 18, 2020 by Michael Mullowney

Dr. Barry O’Keefe is interviewed for BBC documentary Extinction: The Facts. By Mario Figueroa, PhD On September 2020, the BBC released Extinction: The Facts, a documentary about the sixth mass extinction. It is narrated by Sir David Attenborough, a…

Exploring Berry Patches at the Top of the World

October 24, 2020 by Michael Mullowney

The main three indigenous berries around Point Hope, Alaska. (From L to R) Rubus chamaemorus (cloudberry), Vaccinium uliginosum (lowbush blueberry), and Empetrum nigrum (black crowberry). Photo credit: Joshua J. Kellogg. By Joshua J. Kellogg, PhD As natural product researchers, field…