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You are here: Home / Archives for Hot Topics

Hot Topics

HOT TOPICS IN PHARMACOGNOSY: Chemistry and CoV-2 Treatments

April 12, 2021 by ASP Newsletter

By David J. Newman, DPhil INTRODUCTION Over the last eight or so months there have been a series of papers, some short, some long, covering what can be considered as four major topics: natural products, repurposing of approved drugs, use…

Filed Under: 2021, Hot Topics, Newsletters, Spring, Vol 57 Issue 1

HOT TOPICS IN PHARMACOGNOSY: The Evolution of Dolastatin 10 Derivatives as Sources of ADC Warheads

February 8, 2021 by ASP Newsletter

By David Newman, DPhil Though natural product chemists who specialize in marine-sourced agents are usually aware of the contribution of structures based upon dolastatin 10 as warheads in antibody-drug conjugates (ADCs), tarĀ­geted against cancers of varying etiologies, the majority of…

Filed Under: 2020, Hot Topics, Newsletters, Vol 56 Issue 4, Winter

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