by David J. Newman, DPhil

This article appears in the ASP Newsletter Volume 61, Issue 1.

This column will cover a variety of topics culled from a number of recent publications including: potential methodologies against resistant microbes involved in biofilms; recent reports on boron-containing potential antibiotics, some old, some new; organo-metallic (ferrocene-containing) against fungi and neglected tropical diseases (NTDs); a short excursion into the genetics of didemnin B production; and finally a very interesting protein kinase inhibitor, from a marine sample collected under the NCI’s marine collection program, further fractionated under the later NCI’s Program for Natural Products Discovery (NPNPD), and then synthesized-yielding aplithianines A and B.